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  • Overview

    ANCA-associated vasculitis (AAV) is a complex autoimmune disease. This condition can lead to life-threatening complications that primarily affect kidney function due to necrotizing glomerulonephritis. Tune in to find out how to incorporate targeted therapies when managing AAV. Your patients will thank you for joining our experts, Drs. Bernhard Hellmich and David Jayne, in their discussion.

  • Disclosure of Conflicts of Interest

    In accordance with the ACCME Standards for Integrity and Independence, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any ineligible company. GLC mitigates all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

    Host:
    David Jayne, MD
    Professor of Clinical Autoimmunity
    Department of Medicine
    University of Cambridge
    Cambridge, United Kingdom

    Consulting Fees: Amgen, AstraZeneca, Bristol Myers Squibb, CSL Vifor, GSK, Novartis, Roche, Takeda
    Contracted Research: GSK, Roche
    Ownership Interest: Aurinia

    Faculty:
    Bernhard Hellmich, MD
    Chair, Department of Medicine
    Medius Kliniken, University of Tübingen
    Baden-Württemberg, Germany

    Consulting Fees: AbbVie, Astra Zeneca, Boehringer Ingelheim, CSL Vifor, GSK, InflaRx, Janssen, Novartis
    Royalties: AbbVie, Amgen, BMS, Boehringer Ingelheim, CSL Vifor, GSK, InflaRx, Janssen, MSD, Novartis, Pfizer, Phadia, Roche

    Reviewers/Content Planners/Authors:

    • Megan Clem has nothing to disclose.
    • Cindy Davidson has nothing to disclose.
    • Ann Early has nothing to disclose.
    • Howard Green has nothing to disclose. 
    • Amanda Hilferty has nothing to disclose.
    • Hany Ibrahim, MD, has nothing to disclose.
    • Brian P. McDonough, MD, FAAFP, has nothing to disclose.
    • Tim Person has nothing to disclose.
  • Learning Objectives

    After participating in this educational activity, participants should be better able to:

    • Identify the role of the alternative complement pathway in the pathogenesis of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis
    • Contrast efficacy and safety of induction and maintenance therapies in managing patients with ANCA-associated vasculitis
    • Identify patients who may benefit from C5a receptor inhibitors
  • Target Audience

    This activity is designed to meet the educational needs of nephrologists and rheumatologists.

  • Accreditation and Credit Designation Statements

    In support of improving patient care, Global Learning Collaborative (GLC) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

    The American Medical Association has an agreement of mutual recognition of Continuing Medical Education (CME) credits with the European Union of Medical Specialists (UEMS), the accreditation body for European countries. Physicians interested in converting AMA PRA Category 1 CreditsTM to UEMS-European Accreditation Council for Continuing Medical Education CME credits (ECMECs) should contact the UEMS at mutualrecognition@uems.eu.

    Global Learning Collaborative (GLC) designates this enduring activity for a maximum of .25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Global Learning Collaborative (GLC) designates this activity for .25 nursing contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

  • Provider(s)/Educational Partner(s)

    Our ultimate goal is to improve the care being delivered to patients, and our high-quality, evidence-based CME initiatives reflect our dedication to the creation and execution of excellence and are the product of shared research, knowledge, and clinical practice skills across the healthcare continuum.

  • Commercial Support

    This activity is supported by an independent educational grant from CSL Vifor.

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Medtelligence. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience, and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to link to a site outside of Medtelligence you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.

    Reproduction Prohibited
    Reproduction of this material is not permitted without written permission from the copyright owner.

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